PrimePCR™ ddPCR™ Expression Probe Assay: MAN1B1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0054494; exonic

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5041490
Chromosome Location:   9:139990690-139990790question
Amplicon Length:   71

Gene Information

This gene encodes an enzyme belonging to the glycosyl hydrolase 47 family. This enzyme functions in N-glycan biosynthesis and is a class I alpha-12-mannosidase that specifically converts Man9GlcNAc to Man8GlcNAc isomer B. It is required for N-glycan trimming to Man5-6GlcNAc2 in the endoplasmic-reticulum-associated degradation pathway. Mutations in this gene cause autosomal-recessive intellectual disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 11. [provided by RefSeq Dec 2011]

Gene Symbol:   MAN1B1
Gene Name:   mannosidase, alpha, class 1B, member 1
Aliases:   ERMan1, MANA-ER
RefSeq:   NC_000009.11 NT_024000.16
Ensembl:   ENSG00000177239
Entrez:   11253
UniGene:   Hs.279881
Chromosome Mapping:   9q34

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