PrimePCR™ ddPCR™ Expression Probe Assay: SPTBN2, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0054277; exonic

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5041092
Chromosome Location:   11:66473308-66475116question
Amplicon Length:   101

Gene Information

Spectrins are principle components of a cell's membrane-cytoskeleton and are composed of two alpha and two beta spectrin subunits. The protein encoded by this gene (SPTBN2) is called spectrin beta non-erythrocytic 2 or beta-III spectrin. It is related to but distinct from the beta-II spectrin gene which is also known as spectrin beta non-erythrocytic 1 (SPTBN1). SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter EAAT4 at the surface of the plasma membrane. Mutations in this gene cause a form of spinocerebellar ataxia SCA5 that is characterized by neurodegeneration progressive locomotor incoordination dysarthria and uncoordinated eye movements. [provided by RefSeq Dec 2009]

Gene Symbol:   SPTBN2
Gene Name:   spectrin, beta, non-erythrocytic 2
Aliases:   GTRAP41, SCA5
RefSeq:   NC_000011.9 NG_016150.1 NT_167190.1
Ensembl:   ENSG00000173898
Entrez:   6712
UniGene:   Hs.26915
Chromosome Mapping:   11q13

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