PrimePCR™ ddPCR™ Expression Probe Assay: STAT5B, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0054267; exonic

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5041072
Chromosome Location:   17:40379679-40384099question
Amplicon Length:   77

Gene Information

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors STAT family members are phosphorylated by the receptor associated kinases and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands such as IL2 IL4 CSF1 and different growth hormones. It has been shown to be involved in diverse biological processes such as TCR signaling apoptosis adult mammary gland development and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. [provided by RefSeq Jul 2008]

Gene Symbol:   STAT5B
Gene Name:   signal transducer and activator of transcription 5B
Aliases:   STAT5
RefSeq:   NC_000017.10 NG_007271.1 NT_010783.15
Ensembl:   ENSG00000173757
Entrez:   6777
UniGene:   Hs.731529
Chromosome Mapping:   17q11.2

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