This is the amplicon context sequence in accordance with the minimum information for the publication of real-time quantitative PCR experiements (MIQE) guidelines. For more details, please refer to the following publication, "Primer Sequence Disclosure: A Clarification of the MIQE Guidelines."
ddPCR™ probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.
Info: HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0054215; exonic
This gene encodes an enzyme that functions in the final steps in the biosynthesis of CoQ (ubiquinone) a redox carrier in the mitochondrial respiratory chain and a lipid-soluble antioxidant. This enzyme which is part of the coenzyme Q10 pathway catalyzes the prenylation of parahydroxybenzoate with an all-trans polyprenyl group. Mutations in this gene cause coenzyme Q10 deficiency a mitochondrial encephalomyopathy and also COQ2 nephropathy an inherited form of mitochondriopathy with primary renal involvement. [provided by RefSeq Oct 2009]