PrimePCR™ ddPCR™ Expression Probe Assay: PRNP, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0054113; exonic

Fluorophore:   FAM
List Price:    Inquire
Your Price:   Inquire

Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5040804
Chromosome Location:   20:4680284-4680399question
Amplicon Length:   86

Gene Information

The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20 approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease fatal familial insomnia Gerstmann-Straussler disease Huntington disease-like 1 and kuru. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq Jul 2008]

Gene Symbol:   PRNP
Gene Name:   prion protein
Aliases:   ASCR, CD230, CJD, GSS, MGC26679, PRIP, PrP, PrP27-30, PrP33-35C, PrPc, prion
RefSeq:   NC_000020.10 NG_009087.1 NT_011387.8
Ensembl:   ENSG00000171867
Entrez:   5621
UniGene:   Hs.727471
Chromosome Mapping:   20p13

Number Description Download