PrimePCR™ ddPCR™ Expression Probe Assay: FGB, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0054083; exonic

Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5040748
Chromosome Location:   4:155490701-155490807question
Amplicon Length:   77

Gene Information

The protein encoded by this gene is the beta component of fibrinogen a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading display vasoconstrictor and chemotactic activities and are mitogens for several cell types. Mutations in this gene lead to several disorders including afibrinogenemia dysfibrinogenemia hypodysfibrinogenemia and thrombotic tendency. [provided by RefSeq Jul 2008]

Gene Symbol:   FGB
Gene Name:   fibrinogen beta chain
Aliases:   MGC104327, MGC120405
RefSeq:   NC_000004.11 NT_016354.19 NG_008833.1
Ensembl:   ENSG00000171564
Entrez:   2244
UniGene:   Hs.300774
Chromosome Mapping:   4q28

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