PrimePCR™ ddPCR™ Expression Probe Assay: LIMS1, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0053920; exonic

Fluorophore:   HEX
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5040469
Chromosome Location:   2:109300343-109300442question
Amplicon Length:   70

Gene Information

The protein encoded by this gene is an adaptor protein which contains five LIM domains or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2 which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2010]

Gene Symbol:   LIMS1
Gene Name:   LIM and senescent cell antigen-like domains 1
Aliases:   PINCH, PINCH1
RefSeq:   NC_000002.11 NT_022171.15
Ensembl:   ENSG00000169756
Entrez:   3987
UniGene:   Hs.597715
Chromosome Mapping:   2q12.3

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