PrimePCR™ ddPCR™ Expression Probe Assay: ANTXR1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0053909; exonic

Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5040449
Chromosome Location:   2:69329977-69350168question
Amplicon Length:   86

Gene Information

This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin the causative agent of the disease anthrax. The binding of the protective antigen (PA) component of the tripartite anthrax toxin to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell the other two components of anthrax toxin edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq Oct 2008]

Gene Symbol:   ANTXR1
Gene Name:   anthrax toxin receptor 1
Aliases:   ATR, FLJ10601, FLJ11298, FLJ21776, TEM8
RefSeq:   NC_000002.11 NT_022184.15 NG_012649.1
Ensembl:   ENSG00000169604
Entrez:   84168
UniGene:   Hs.165859
Chromosome Mapping:   2p13.1

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