PrimePCR™ ddPCR™ Expression Probe Assay: GDNF, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0053828; exonic

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5040307
Chromosome Location:   5:37815945-37816047question
Amplicon Length:   73

Gene Information

This gene encodes a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture and was able to prevent apoptosis of motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene may be associated with Hirschsprung disease. [provided by RefSeq Jun 2010]

Gene Symbol:   GDNF
Gene Name:   glial cell derived neurotrophic factor
Aliases:   ATF1, ATF2, HFB1-GDNF, HSCR3
RefSeq:   NC_000005.9 NG_011675.2 NT_006576.16
Ensembl:   ENSG00000168621
Entrez:   2668
UniGene:   Hs.248114
Chromosome Mapping:   5p13.1-p12

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