PrimePCR™ ddPCR™ Expression Probe Assay: HFE2, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0053818; exonic

Fluorophore:   HEX
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5040289
Chromosome Location:   1:145417351-145417480question
Amplicon Length:   100

Gene Information

The product of this gene is involved in iron metabolism. It may be a component of the signaling pathway which activates hepcidin or it may act as a modulator of hepcidin expression. It could also represent the cellular receptor for hepcidin. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Defects in this gene are the cause of hemochromatosis type 2A also called juvenile hemochromatosis (JH). JH is an early-onset autosomal recessive disorder due to severe iron overload resulting in hypogonadotrophic hypogonadism hepatic fibrosis or cirrhosis and cardiomyopathy occurring typically before age of 30. [provided by RefSeq Jul 2008]

Gene Symbol:   HFE2
Gene Name:   hemochromatosis type 2 (juvenile)
Aliases:   HFE2A, HJV, JH, MGC23953, RGMC
RefSeq:   NC_000001.10 NT_167185.1 NG_011568.1
Ensembl:   ENSG00000168509
Entrez:   148738
UniGene:   Hs.632436
Chromosome Mapping:   1q21.1

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