PrimePCR™ ddPCR™ Expression Probe Assay: PDHB, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0053800; exonic

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5040255
Chromosome Location:   3:58413456-58413595question
Amplicon Length:   110

Gene Information

The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and carbon dioxide and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1) dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 beta subunit. Mutations in this gene are associated with pyruvate dehydrogenase E1-beta deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq Mar 2012]

Gene Symbol:   PDHB
Gene Name:   pyruvate dehydrogenase (lipoamide) beta
Aliases:   DKFZp564K0164, PHE1B
RefSeq:   NC_000003.11 NG_016860.1 NT_022517.18
Ensembl:   ENSG00000168291
Entrez:   5162
UniGene:   Hs.161357
Chromosome Mapping:   3p21.1-p14.2

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