PrimePCR™ ddPCR™ Expression Probe Assay: CTNNB1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0053779; exonic

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5040215
Chromosome Location:   3:41266084-41266226question
Amplicon Length:   113

Gene Information

The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally this protein binds to the product of the APC gene which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC) pilomatrixoma (PTR) medulloblastoma (MDB) and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.[provided by RefSeq Oct 2009]

Gene Symbol:   CTNNB1
Gene Name:   catenin (cadherin-associated protein), beta 1, 88kDa
Aliases:   CTNNB, DKFZp686D02253, FLJ25606, FLJ37923
RefSeq:   NC_000003.11 NT_022517.18 NG_013302.1
Ensembl:   ENSG00000168036
Entrez:   1499
UniGene:   Hs.476018
Chromosome Mapping:   3p21

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