PrimePCR™ ddPCR™ Expression Probe Assay: SOST, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0053767; exonic

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5040190
Chromosome Location:   17:41831530-41831644question
Amplicon Length:   85

Gene Information

Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder sclerosteosis which causes progressive bone overgrowth. A deletion downstream of this gene which causes reduced sclerostin expression is associated with a milder form of the disorder called van Buchem disease. [provided by RefSeq Jul 2008]

Gene Symbol:   SOST
Gene Name:   sclerostin
Aliases:   VBCH
RefSeq:   NC_000017.10 NG_008078.2 NT_010783.15
Ensembl:   ENSG00000167941
Entrez:   50964
UniGene:   Hs.349204
Chromosome Mapping:   17q11.2

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