PrimePCR™ ddPCR™ Expression Probe Assay: CYP7A1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0053764; exonic

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5040186
Chromosome Location:   8:59403834-59403942question
Amplicon Length:   79

Gene Information

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver which converts cholesterol to bile acids. This reaction is the rate limiting step and the major site of regulation of bile acid synthesis which is the primary mechanism for the removal of cholesterol from the body. Polymorphisms in the promoter of this gene are associated with defects in bile acid synthesis. [provided by RefSeq Feb 2010]

Gene Symbol:   CYP7A1
Gene Name:   cytochrome P450, family 7, subfamily A, polypeptide 1
Aliases:   CP7A, CYP7, CYPVII, MGC126826, MGC138389
RefSeq:   NC_000008.10 NG_007969.1 NT_008183.19
Ensembl:   ENSG00000167910
Entrez:   1581
UniGene:   Hs.1644
Chromosome Mapping:   8q11-q12

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