PrimePCR™ ddPCR™ Expression Probe Assay: GREM1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0053682; exonic

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5040049
Chromosome Location:   15:33023348-33023450question
Amplicon Length:   73

Gene Information

This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists to which this gene belongs is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP this gene may play a role in regulating organogenesis body patterning and tissue differentiation. In mouse this protein has been shown to relay the sonic hedgehog (SHH) signal from the polarizing region to the apical ectodermal ridge during limb bud outgrowth. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2010]

Gene Symbol:   GREM1
Gene Name:   gremlin 1
Aliases:   CKTSF1B1, DAND2, DRM, GREMLIN, IHG-2, MGC126660
RefSeq:   NC_000015.9 NT_010194.17
Ensembl:   ENSG00000166923
Entrez:   26585
UniGene:   Hs.40098
Chromosome Mapping:   15q13.3

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