This is the amplicon context sequence in accordance with the minimum information for the publication of real-time quantitative PCR experiements (MIQE) guidelines. For more details, please refer to the following publication, "Primer Sequence Disclosure: A Clarification of the MIQE Guidelines."
ddPCR™ probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.
Info: HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0053563; exonic
MARCH8 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 18.104.22.168). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins thereby signaling their vesicular transport between membrane compartments. MARCH8 induces the internalization of several membrane glycoproteins (Goto et al. 2003 [PubMed 12582153]; Bartee et al. 2004 [PubMed 14722266]).[supplied by OMIM Apr 2010]