PrimePCR™ ddPCR™ Expression Probe Assay: CTSB, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0053506; exonic

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5039710
Chromosome Location:   8:11708397-11708486question
Amplicon Length:   60

Gene Information

The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease the most common cause of dementia. Overexpression of the encoded protein which is a member of the peptidase C1 family has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   CTSB
Gene Name:   cathepsin B
Aliases:   APPS, CPSB
RefSeq:   NC_000008.10 NT_077531.4 NG_009217.1
Ensembl:   ENSG00000164733
Entrez:   1508
UniGene:   Hs.520898
Chromosome Mapping:   8p22

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