PrimePCR™ ddPCR™ Expression Probe Assay: LMTK2, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0053504; exonic

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5039706
Chromosome Location:   7:97835898-97836026question
Amplicon Length:   99

Gene Information

The protein encoded by this gene belongs to the protein kinase superfamily and the protein tyrosine kinase family. It contains N-terminal transmembrane helices and a long C-terminal cytoplasmic tail with serine/threonine/tyrosine kinase activity. This protein interacts with several other proteins such as Inhibitor-2 (Inh2) protein phosphatase-1 (PP1C) p35 and myosin VI. It phosporylates other proteins and is itself also phosporylated when interacting with cyclin-dependent kinase 5 (cdk5)/p35 complex. This protein involves in nerve growth factor (NGF)-TrkA signalling and also plays a critical role in endosomal membrane trafficking. Mouse studies suggested an essential role of this protein in spermatogenesis. [provided by RefSeq Oct 2009]

Gene Symbol:   LMTK2
Gene Name:   lemur tyrosine kinase 2
Aliases:   AATYK2, BREK, FLJ46659, KIAA1079, KPI-2, KPI2, LMR2, cprk
RefSeq:   NC_000007.13 NG_013375.1 NT_007933.15
Ensembl:   ENSG00000164715
Entrez:   22853
UniGene:   Hs.444179
Chromosome Mapping:   7q21.3

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