PrimePCR™ ddPCR™ Expression Probe Assay: CAMLG, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0053495; exonic

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5039689
Chromosome Location:   5:134086948-134087048question
Amplicon Length:   71

Gene Information

The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway implicating cyclophilin B in calcium signaling even in the absence of cyclosporin. [provided by RefSeq Jul 2008]

Gene Symbol:   CAMLG
Gene Name:   calcium modulating ligand
Aliases:   CAML, MGC163197
RefSeq:   NC_000005.9 NT_034772.6
Ensembl:   ENSG00000164615
Entrez:   819
UniGene:   Hs.529846
Chromosome Mapping:   5q23

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