PrimePCR™ ddPCR™ Expression Probe Assay: GRIK2, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0053483; exonic

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5039665
Chromosome Location:   6:102250307-102266353question
Amplicon Length:   86

Gene Information

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation. [provided by RefSeq Jul 2008]

Gene Symbol:   GRIK2
Gene Name:   glutamate receptor, ionotropic, kainate 2
Aliases:   EAA4, GLR6, GLUK6, GLUR6, MGC74427, MRT6
RefSeq:   NC_000006.11 NT_025741.15 NG_009224.2
Ensembl:   ENSG00000164418
Entrez:   2898
UniGene:   Hs.98262
Chromosome Mapping:   6q16.3-q21

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