PrimePCR™ ddPCR™ Expression Probe Assay: NDUFS4, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0053460; exonic

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5039622
Chromosome Location:   5:52954438-52979068question
Amplicon Length:   108

Gene Information

This gene encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) or NADH:ubiquinone oxidoreductase the first multi-subunit enzyme complex of the mitochondrial respiratory chain. Complex I plays a vital role in cellular ATP production the primary source of energy for many crucial processes in living cells. It removes electrons from NADH and passes them by a series of different protein-coupled redox centers to the electron acceptor ubiquinone. In well-coupled mitochondria the electron flux leads to ATP generation via the building of a proton gradient across the inner membrane. Complex I is composed of at least 41 subunits of which 7 are encoded by the mitochondrial genome and the remainder by nuclear genes. [provided by RefSeq Jul 2008]

Gene Symbol:   NDUFS4
Gene Name:   NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
Aliases:   AQDQ, CI-18
RefSeq:   NC_000005.9 NG_008200.1 NT_006713.15
Ensembl:   ENSG00000164258
Entrez:   4724
UniGene:   Hs.528222
Chromosome Mapping:   5q11.1

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