PrimePCR™ ddPCR™ Expression Probe Assay: IL15, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0053444; exonic

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5039594
Chromosome Location:   4:142654093-142654227question
Amplicon Length:   105

Gene Information

The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits and may compete for the same receptor and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases as well as the phosphorylation and activation of transcription activators STAT3 STAT5 and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L) possibly through the transcription activation activity of STAT6 and thus prevent apoptosis. Alternatively spliced transcript variants of this gene have been reported. [provided by RefSeq Feb 2011]

Gene Symbol:   IL15
Gene Name:   interleukin 15
Aliases:   IL-15, MGC9721
RefSeq:   NC_000004.11 NT_016354.19
Ensembl:   ENSG00000164136
Entrez:   3600
UniGene:   Hs.168132
Chromosome Mapping:   4q31

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