PrimePCR™ ddPCR™ Expression Probe Assay: PTPN13, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0053373; exonic

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5039471
Chromosome Location:   4:87593571-87607880question
Amplicon Length:   114

Gene Information

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth differentiation mitotic cycle and oncogenic transformation. This PTP is a large intracellular protein. It has a catalytic PTP domain at its C-terminus and two major structural domains: a region with five PDZ domains and a FERM domain that binds to plasma membrane and cytoskeletal elements. This PTP was found to interact with and dephosphorylate Fas receptor and IkappaBalpha through the PDZ domains. This suggests it has a role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein and thus may function as a regulator of Rho signaling pathways. Four alternatively spliced transcript variants which encode distinct proteins have been reported. [provided by RefSeq Oct 2008]

Gene Symbol:   PTPN13
Gene Name:   protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
Aliases:   DKFZp686J1497, FAP-1, PNP1, PTP-BAS, PTP-BL, PTP1E, PTPL1, PTPLE
RefSeq:   NC_000004.11 NT_016354.19
Ensembl:   ENSG00000163629
Entrez:   5783
UniGene:   Hs.436142
Chromosome Mapping:   4q21.3

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