PrimePCR™ ddPCR™ Expression Probe Assay: PYHIN1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0053364; exonic

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5039452
Chromosome Location:   1:158908231-158908329question
Amplicon Length:   69

Gene Information

The protein encoded by this gene belongs to the HIN-200 family of interferon-inducible proteins that share a 200-amino acid signature motif at their C-termini. HIN200 proteins are primarily nuclear and are involved in transcriptional regulation of genes important for cell cycle control differentiation and apoptosis. Downregulation of this gene is associated with breast cancer. This protein acts as a tumor suppressor by promoting ubiquitination and subsequent degradation of MDM2 which leads to stabilization of p53/TP53. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq Aug 2011]

Gene Symbol:   PYHIN1
Gene Name:   pyrin and HIN domain family, member 1
Aliases:   IFIX, MGC23885, RP11-520H16.1
RefSeq:   NC_000001.10 NT_004487.19
Ensembl:   ENSG00000163564
Entrez:   149628
UniGene:   Hs.734876
Chromosome Mapping:   1q23.1

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