PrimePCR™ ddPCR™ Expression Probe Assay: CRYBA2, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0053351; exonic

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5039428
Chromosome Location:   2:219855610-219855705question
Amplicon Length:   66

Gene Information

Crystallins are separated into two classes: taxon-specific or enzyme and ubiquitous. The latter class constitutes the major proteins of the vertebrate eye which function to maintain the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development these crystallins are made and then retained throughout life making them extremely stable proteins. Mammalian lens crystallins are divided into alpha beta and gamma families; beta and gamma crystallins are also defined as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs a connecting peptide and N- and C-terminal extensions. Beta-crystallins the most heterogeneous differ by the presence of the C-terminal extension (present in the basic group but absent in the acidic group). Beta-crystallins form aggregates of different sizes and are able to form homodimers through self-association or heterodimers with other beta-crystallins. This gene is a beta acidic group member. Three alternatively spliced transcript variants encoding identical proteins have been reported. [provided by RefSeq Jul 2008]

Gene Symbol:   CRYBA2
Gene Name:   crystallin, beta A2
Aliases:   Not Available
RefSeq:   NC_000002.11 NG_023323.1 NT_005403.17
Ensembl:   ENSG00000163499
Entrez:   1412
UniGene:   Hs.415790
Chromosome Mapping:   2q34-q36

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