This is the amplicon context sequence in accordance with the minimum information for the publication of real-time quantitative PCR experiements (MIQE) guidelines. For more details, please refer to the following publication, "Primer Sequence Disclosure: A Clarification of the MIQE Guidelines."
ddPCR™ probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.
Info: HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0053286; exonic
The REL gene encodes c-Rel a transcription factor that is a member of the Rel/NFKB family which also includes RELA (MIM 164014) RELB (604758) NFKB1 (MIM 164011) and NFKB2 (MIM 164012). These proteins are related through a highly conserved N-terminal region termed the 'Rel domain' which is responsible for DNA binding dimerization nuclear localization and binding to the NFKB inhibitor (MIM 164008) (Belguise and Sonenshein 2007 [PubMed 18037997]).[supplied by OMIM May 2008]