PrimePCR™ ddPCR™ Expression Probe Assay: PRKAA2, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0053240; exonic

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5039222
Chromosome Location:   1:57169806-57169904question
Amplicon Length:   69

Gene Information

The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses AMPK is activated and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR) key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq Jul 2008]

Gene Symbol:   PRKAA2
Gene Name:   protein kinase, AMP-activated, alpha 2 catalytic subunit
Aliases:   AMPK, AMPK2, PRKAA
RefSeq:   NC_000001.10 NT_032977.9
Ensembl:   ENSG00000162409
Entrez:   5563
UniGene:   Hs.437039
Chromosome Mapping:   1p31

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