PrimePCR™ ddPCR™ Expression Probe Assay: LRP5, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0053235; exonic

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5039214
Chromosome Location:   11:68216371-68216520question
Amplicon Length:   120

Gene Information

This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. [provided by RefSeq Nov 2009]

Gene Symbol:   LRP5
Gene Name:   low density lipoprotein receptor-related protein 5
Aliases:   BMND1, EVR1, EVR4, HBM, LR3, LRP7, OPPG, OPS, OPTA1, VBCH2
RefSeq:   NC_000011.9 NG_015835.1 NT_167190.1
Ensembl:   ENSG00000162337
Entrez:   4041
UniGene:   Hs.6347
Chromosome Mapping:   11q13.4

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