PrimePCR™ ddPCR™ Expression Probe Assay: CYP3A7, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0053178; exonic

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5039114
Chromosome Location:   7:99303022-99303134question
Amplicon Length:   83

Gene Information

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate which is involved in the formation of estriol during pregnancy. The enzyme also metabolizes some drugs such as aflatoxin B1. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Transcript variants have been described but it is not known whether these transcripts are normally produced. This gene undergoes readthrough transcription with the downstream CYP3AP1 pseudogene resulting in an isoform with a novel C-terminus as represented in GeneID:100861540. [provided by RefSeq Feb 2012]

Gene Symbol:   CYP3A7
Gene Name:   cytochrome P450, family 3, subfamily A, polypeptide 7
Aliases:   CP37, P450-HFLA
RefSeq:   NC_000007.13 NG_000004.3 NG_007983.1 NT_007933.15
Ensembl:   ENSG00000160870
Entrez:   1551
UniGene:   Hs.111944
Chromosome Mapping:   7q21-q22.1

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