PrimePCR™ ddPCR™ Expression Probe Assay: IL6R, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0053168; exonic

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5039094
Chromosome Location:   1:154407563-154408469question
Amplicon Length:   65

Gene Information

This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta) a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases such as multiple myeloma autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.[provided by RefSeq May 2011]

Gene Symbol:   IL6R
Gene Name:   interleukin 6 receptor
Aliases:   CD126, IL-6R-1, IL-6RA, IL6RA, MGC104991, gp80
RefSeq:   NC_000001.10 NG_012087.1 NT_004487.19
Ensembl:   ENSG00000160712
Entrez:   3570
UniGene:   Hs.135087
Chromosome Mapping:   1q21

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