PrimePCR™ ddPCR™ Expression Probe Assay: PCSK7, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0053164; exonic

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5039087
Chromosome Location:   11:117100549-117101161question
Amplicon Length:   91

Gene Information

The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease. It is structurally related to its family members PACE and PACE4. This protein is concentrated in the trans-Golgi network associated with the membranes and is not secreted. It can process proalbumin and is thought to be responsible for the activation of HIV envelope glycoproteins gp160 and gp140. This gene has been implicated in the transcriptional regulation of housekeeping genes. Multiple alternatively spliced transcripts are described for this gene but their full length nature is not yet known. Downstream of this gene's map location at 11q23-q24 nucleotides that match part of this gene's 3' end are duplicated and inverted. A translocation breakpoint associated with lymphoma occurs between this gene and its inverted counterpart. [provided by RefSeq Jul 2008]

Gene Symbol:   PCSK7
Gene Name:   proprotein convertase subtilisin/kexin type 7
Aliases:   FLJ23503, FLJ45329, LPC, PC7, PC8, SPC7
RefSeq:   NC_000011.9 NT_033899.8
Ensembl:   ENSG00000160613
Entrez:   9159
UniGene:   Hs.648612
Chromosome Mapping:   11q23-q24

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