PrimePCR™ ddPCR™ Expression Probe Assay: TNFRSF13C, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0053132; exonic

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5039028
Chromosome Location:   22:42321111-42321212question
Amplicon Length:   72

Gene Information

B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also some SLE patients have increased levels of BAFF in serum. Therefore it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival. [provided by RefSeq Jul 2008]

Gene Symbol:   TNFRSF13C
Gene Name:   tumor necrosis factor receptor superfamily, member 13C
Aliases:   BAFF-R, BAFFR, CD268, CVID4, MGC138235
RefSeq:   NC_000022.10 NG_007579.1 NT_011520.12
Ensembl:   ENSG00000159958
Entrez:   115650
UniGene:   Hs.344088
Chromosome Mapping:   22q13.1-q13.31

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