PrimePCR™ ddPCR™ Expression Probe Assay: NPR2, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0053130; exonic

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5039025
Chromosome Location:   9:35806122-35806398question
Amplicon Length:   89

Gene Information

This gene encodes natriuretic peptide receptor B one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain a single membrane-spanning region and intracellularly a protein kinase homology domain a helical hinge region involved in oligomerization and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP) which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type. [provided by RefSeq Jul 2008]

Gene Symbol:   NPR2
Gene Name:   natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
RefSeq:   NC_000009.11 NG_009249.1 NT_008413.18
Ensembl:   ENSG00000159899
Entrez:   4882
UniGene:   Hs.78518
Chromosome Mapping:   9p21-p12

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