PrimePCR™ ddPCR™ Expression Probe Assay: UBR1, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0053118; exonic

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5039001
Chromosome Location:   15:43317033-43317150question
Amplicon Length:   88

Gene Information

The N-end rule pathway is one proteolytic pathway of the ubiquitin system. The recognition component of this pathway encoded by this gene binds to a destabilizing N-terminal residue of a substrate protein and participates in the formation of a substrate-linked multiubiquitin chain. This leads to the eventual degradation of the substrate protein. The protein described in this record has a RING-type zinc finger and a UBR-type zinc finger. Mutations in this gene have been associated with Johanson-Blizzard syndrome. [provided by RefSeq Jul 2008]

Gene Symbol:   UBR1
Gene Name:   ubiquitin protein ligase E3 component n-recognin 1
Aliases:   JBS, MGC142065, MGC142067
RefSeq:   NC_000015.9 NG_012182.1 NT_010194.17
Ensembl:   ENSG00000159459
Entrez:   197131
UniGene:   Hs.591121
Chromosome Mapping:   15q13

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