PrimePCR™ ddPCR™ Expression Probe Assay: MRPL10, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0053103; exonic

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5038975
Chromosome Location:   17:45901001-45901097question
Amplicon Length:   67

Gene Information

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species the proteins comprising the mitoribosome differ greatly in sequence and sometimes in biochemical properties which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified three transcript variants that encode two different isoforms. A pseudogene corresponding to this gene is found on chromosome 5q. [provided by RefSeq Nov 2010]

Gene Symbol:   MRPL10
Gene Name:   mitochondrial ribosomal protein L10
Aliases:   L10MT, MGC17973, MRP-L10, MRP-L8, MRPL8, RPML8
RefSeq:   NC_000017.10 NT_010783.15
Ensembl:   ENSG00000159111
Entrez:   124995
UniGene:   Hs.347535
Chromosome Mapping:   17q21.32

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