This is the amplicon context sequence in accordance with the minimum information for the publication of real-time quantitative PCR experiements (MIQE) guidelines. For more details, please refer to the following publication, "Primer Sequence Disclosure: A Clarification of the MIQE Guidelines."
ddPCR™ probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.
Info: HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0053060; exonic
The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain a NACHT-associated domain (NAD) a C-terminal leucine-rich repeat (LRR) region and an N-terminal pyrin domain (PYD). This protein may play a regulatory role in the innate immune system as similar family members belong to the signal-induced multiprotein complex the inflammasome that activates the pro-inflammatory caspases caspase-1 and caspase-5. [provided by RefSeq Jul 2008]