PrimePCR™ ddPCR™ Expression Probe Assay: RNF20, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0052954; exonic

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5038708
Chromosome Location:   9:104302523-104302612question
Amplicon Length:   60

Gene Information

The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast this protein also suppresses the expression of several protooncogenes and growth-related genes including many genes that are induced by epidermal growth factor. This gene selectively suppresses the expression of some genes by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS). [provided by RefSeq Feb 2012]

Gene Symbol:   RNF20
Gene Name:   ring finger protein 20
Aliases:   BRE1, BRE1A, FLJ11189, FLJ20382, KIAA2779, MGC129667, MGC129668, hBRE1
RefSeq:   NC_000009.11 NT_008470.19
Ensembl:   ENSG00000155827
Entrez:   56254
UniGene:   Hs.729085
Chromosome Mapping:   9q22

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