PrimePCR™ ddPCR™ Expression Probe Assay: TCEB1, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0052903; exonic

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5038615
Chromosome Location:   8:74858759-74858944question
Amplicon Length:   156

Gene Information

This gene encodes the protein elongin C which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2 B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C and thereby inhibits transcription elongation. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been identified. [provided by RefSeq Mar 2011]

Gene Symbol:   TCEB1
Gene Name:   transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
Aliases:   SIII
RefSeq:   NC_000008.10 NG_016618.1 NT_008183.19
Ensembl:   ENSG00000154582
Entrez:   6921
UniGene:   Hs.731928
Chromosome Mapping:   8q21.11

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