PrimePCR™ ddPCR™ Expression Probe Assay: CAST, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0052853; exonic

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5038525
Chromosome Location:   5:96100959-96101780question
Amplicon Length:   65

Gene Information

The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4) and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq Jun 2010]

Gene Symbol:   CAST
Gene Name:   calpastatin
Aliases:   BS-17, MGC9402
RefSeq:   NC_000005.9 NG_027839.1 NT_034772.6
Ensembl:   ENSG00000153113
Entrez:   831
UniGene:   Hs.436186
Chromosome Mapping:   5q15

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