PrimePCR™ ddPCR™ Expression Probe Assay: GRIA4, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0052833; exonic

Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5038486
Chromosome Location:   11:105483004-105483132question
Amplicon Length:   99

Gene Information

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia. [provided by RefSeq Jul 2008]

Gene Symbol:   GRIA4
Gene Name:   glutamate receptor, ionotrophic, AMPA 4
Aliases:   GLUR4, GLUR4C, GLURD, GluA4
RefSeq:   NC_000011.9 NT_033899.8
Ensembl:   ENSG00000152578
Entrez:   2893
UniGene:   Hs.503743
Chromosome Mapping:   11q22

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