PrimePCR™ ddPCR™ Expression Probe Assay: PTPRO, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0052783; exonic

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5038401
Chromosome Location:   12:15739843-15739982question
Amplicon Length:   110

Gene Information

This gene encodes a member of the R3 subtype family of receptor-type protein tyrosine phosphatases. These proteins are localized to the apical surface of polarized cells and may have tissue-specific functions through activation of Src family kinases. This gene contains two distinct promoters and alternatively spliced transcript variants encoding multiple isoforms have been observed. The encoded proteins may have multiple isoform-specific and tissue-specific functions including the regulation of osteoclast production and activity inhibition of cell proliferation and facilitation of apoptosis. This gene is a candidate tumor suppressor and decreased expression of this gene has been observed in several types of cancer. [provided by RefSeq May 2011]

Gene Symbol:   PTPRO
Gene Name:   protein tyrosine phosphatase, receptor type, O
Aliases:   GLEPP1, PTP-U2, PTP-oc, PTPU2
RefSeq:   NC_000012.11 NT_009714.17
Ensembl:   ENSG00000151490
Entrez:   5800
UniGene:   Hs.160871
Chromosome Mapping:   12p13.3-p13.2,12p13-p12

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