PrimePCR™ ddPCR™ Expression Probe Assay: UPF2, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0052778; exonic

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5038391
Chromosome Location:   10:11963178-11963284question
Amplicon Length:   77

Gene Information

This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene; both variants encode the same protein. [provided by RefSeq Jul 2008]

Gene Symbol:   UPF2
Gene Name:   UPF2 regulator of nonsense transcripts homolog (yeast)
Aliases:   DKFZp434D222, HUPF2, KIAA1408, MGC138834, MGC138835, RENT2, smg-3
RefSeq:   NC_000010.10 NT_008705.16
Ensembl:   ENSG00000151461
Entrez:   26019
UniGene:   Hs.370689
Chromosome Mapping:   10p14-p13

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