PrimePCR™ ddPCR™ Expression Probe Assay: CACNA1C, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0052759; exonic

 
Fluorophore:   HEX
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5038361
Chromosome Location:   12:2690767-2690902question
Amplicon Length:   106

Gene Information

This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1 alpha-2/delta beta and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. [provided by RefSeq Jul 2008]

Gene Symbol:   CACNA1C
Gene Name:   calcium channel, voltage-dependent, L type, alpha 1C subunit
Aliases:   CACH2, CACN2, CACNL1A1, CCHL1A1, CaV1.2, MGC120730, TS
RefSeq:   NC_000012.11 NT_009759.16 NG_008801.1
Ensembl:   ENSG00000151067
Entrez:   775
UniGene:   Hs.118262
Chromosome Mapping:   12p13.3

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