PrimePCR™ ddPCR™ Expression Probe Assay: SLC7A11, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0052756; exonic

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5038355
Chromosome Location:   4:139092819-139092946question
Amplicon Length:   98

Gene Information

This gene encodes a member of a heteromeric sodium-independent anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system designated Xc(-) the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels resulting in neuronal cell death. [provided by RefSeq Sep 2011]

Gene Symbol:   SLC7A11
Gene Name:   solute carrier family 7, (cationic amino acid transporter, y+ system) member 11
Aliases:   CCBR1, xCT
RefSeq:   NC_000004.11 NT_016354.19
Ensembl:   ENSG00000151012
Entrez:   23657
UniGene:   Hs.390594
Chromosome Mapping:   4q28-q32

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