PrimePCR™ ddPCR™ Expression Probe Assay: ADRA2A, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0052744; exonic

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5038338
Chromosome Location:   10:112837299-112837430question
Amplicon Length:   102

Gene Information

Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A alpha2B and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons; the alpha2A subtype inhibited transmitter release at high stimulation frequencies whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes alpha2A subtype and it contains no introns in either its coding or untranslated sequences. [provided by RefSeq Jul 2008]

Gene Symbol:   ADRA2A
Gene Name:   adrenergic, alpha-2A-, receptor
RefSeq:   NC_000010.10 NG_012020.1 NT_030059.13
Ensembl:   ENSG00000150594
Entrez:   150
UniGene:   Hs.249159
Chromosome Mapping:   10q24-q26

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