PrimePCR™ ddPCR™ Expression Probe Assay: PTPRJ, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0052702; exonic

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5038274
Chromosome Location:   11:48142678-48142796question
Amplicon Length:   89

Gene Information

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth differentiation mitotic cycle and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats a single transmembrane region and a single intracytoplasmic catalytic domain and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   PTPRJ
Gene Name:   protein tyrosine phosphatase, receptor type, J
Aliases:   CD148, DEP1, HPTPeta, R-PTP-ETA, SCC1
RefSeq:   NC_000011.9 NT_009237.18 NG_012209.1
Ensembl:   ENSG00000149177
Entrez:   5795
UniGene:   Hs.318547
Chromosome Mapping:   11p11.2

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