PrimePCR™ ddPCR™ Expression Probe Assay: KLHL3, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0052566; exonic

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5038030
Chromosome Location:   5:136993877-136997619question
Amplicon Length:   79

Gene Information

This gene is ubiquitously expressed and encodes a full-length protein which has an N-terminal BTB domain followed by a BACK domain and six kelch-like repeats in the C-terminus. These kelch-like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin-RING E3 ubiquitin ligase (CRL) complex. Muatations in this gene cause pseudohypoaldosteronism type IID (PHA2D); a rare Mendelian syndrome featuring hypertension hyperkalaemia and metabolic acidosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq Mar 2012]

Gene Symbol:   KLHL3
Gene Name:   kelch-like 3 (Drosophila)
Aliases:   FLJ40871, KIAA1129, MGC44594
RefSeq:   NC_000005.9 NT_034772.6
Ensembl:   ENSG00000146021
Entrez:   26249
UniGene:   Hs.655084
Chromosome Mapping:   5q31

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