PrimePCR™ ddPCR™ Expression Probe Assay: MARCH1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0052529; exonic

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5037963
Chromosome Location:   4:164450180-164466862question
Amplicon Length:   104

Gene Information

MARCH1 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins thereby signaling their vesicular transport between membrane compartments. MARCH1 downregulates the surface expression of major histocompatibility complex (MHC) class II molecules (see MIM 142880) and other glycoproteins by directing them to the late endosomal/lysosomal compartment (Bartee et al. 2004 [PubMed 14722266]; Thibodeau et al. 2008 [PubMed 18389477]; De Gassart et al. 2008 [PubMed 18305173]).[supplied by OMIM Mar 2010]

Gene Symbol:   MARCH1
Gene Name:   membrane-associated ring finger (C3HC4) 1
Aliases:   DKFZp564M1682, FLJ20668, MARCH-I, RNF171
RefSeq:   NC_000004.11 NT_016354.19
Ensembl:   ENSG00000145416
Entrez:   55016
UniGene:   Hs.592804
Chromosome Mapping:   4q32.2

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