PrimePCR™ ddPCR™ Expression Probe Assay: ANK2, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0052526; exonic

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5037957
Chromosome Location:   4:114267060-114269447question
Amplicon Length:   105

Gene Information

This gene encodes a member of the ankyrin family of proteins that link the integral membrane proteins to the underlying spectrin-actin cytoskeleton. Ankyrins play key roles in activities such as cell motility activation proliferation contact and the maintenance of specialized membrane domains. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats; a central region with a highly conserved spectrin binding domain; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. The protein encoded by this gene is required for targeting and stability of Na/Ca exchanger 1 in cardiomyocytes. Mutations in this gene cause long QT syndrome 4 and cardiac arrhythmia syndrome. Multiple transcript variants encoding different isoforms have been described. [provided by RefSeq Dec 2011]

Gene Symbol:   ANK2
Gene Name:   ankyrin 2, neuronal
Aliases:   DKFZp686M09125, DKFZp686P0948, FLJ38277, LQT4
RefSeq:   NC_000004.11 NG_009006.1 NT_016354.19
Ensembl:   ENSG00000145362
Entrez:   287
UniGene:   Hs.620557
Chromosome Mapping:   4q25-q27

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