PrimePCR™ ddPCR™ Expression Probe Assay: UBA3, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0052482; exonic

 
Fluorophore:   HEX
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5037885
Chromosome Location:   3:69104590-69105012question
Amplicon Length:   68

Gene Information

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes or E1s ubiquitin-conjugating enzymes or E2s and ubiquitin-protein ligases or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1 an amyloid beta precursor protein binding protein to form a heterodimer and then the enzyme complex activates NEDD8 a ubiquitin-like protein which regulates cell division signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   UBA3
Gene Name:   ubiquitin-like modifier activating enzyme 3
Aliases:   DKFZp566J164, MGC22384, UBE1C, hUBA3
RefSeq:   NC_000003.11 NT_022459.15
Ensembl:   ENSG00000144744
Entrez:   9039
UniGene:   Hs.154320
Chromosome Mapping:   3p24.3-p13

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